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KMID : 0363219950330010172
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Korean Journal of Dermatology
1995 Volume.33 No. 1 p.172 ~ p.178
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A Case of Primary Disseminated Cutaneous Aspergillosis in Chronic active Hepatitis
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Abstract
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An 41-year-old woman with chronic active hepatitis developed multiple asymptomatic erythematous papules, plaques and purpuras on the both lower leg, feet, forearms and hands. Some lesions progressed to ulcers with central black colored necrotic
eschars.
Biopsies and cultures demonstrated a fungus, aspergillus fumigatus, as the etilogic agent. No evidence of involvement of other organs by aspergillus fumigatus was found.
Intravenous amphotericin B therapy was discontinued because of the immediate adverse effects. The patient received treatment with oral itaconazole (200mg/day) and intravenous fluconazole(400mg/day), but skin lesions have been recurring
repeatedly.(Kor J
Dermatol 1995 ; 33(1) : 172~178)
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